Indication Antibacterial Antifungal PJP prophylaxis Antiviral Duration of Prophylaxis ma ixazomib) High dose steroids3 No routine prophylaxis No routine prophylaxis TMP
In our institution, most physicians have prescribed trimethoprim-sulfamethoxazole (TMP-SMX) for primary PJP prophylaxis at a dose of one single-strength tablet per day, or one double-strength
Acne Vulgaris (Off-label) 1 DS tab or 1 regular-strength tab PO qDay or q12hr for up to 18 weeks
(See 'Treatment of erysipelas' above
Prescription pattern and side effects of trimethoprim–sulfamethoxazole
33%, further details see online supplementary table S4 Corticosteroid Use and Pneumocystis Pneumonia Prophylaxis: A Teachable Moment
Pneumocystis carinii pneumonia (PCP), now referred to as Pneumocystis jirovecii pneumonia, is a fungal infection that most commonly affects the immunocompromised and, in some cases, can be severely life-threatening
Trimethoprim-sulfamethoxazole (TMP-SMX) is the recommended first-line prophylactic agent for PJP, is effective and usually well-tolerated, although serious adverse reactions to the sulfa moiety can occur
The presence of SBP, which almost always occurs in patients with cirrhosis and ascites, is suspected because of signs and symptoms such as fever, abdominal pain, or altered mental status ( table 1 )
5 to 7
GCs may sometimes be tapered to complete discontinuation
28